3,4-Difluoronitrobenzene is a unique chemical structure characterized by a benzene ring substituted with two fluorine atoms at the 3 and 4 positions, along with a nitro group (-NO2) attached to the ring. This compound exhibits notable reactivity due to the electron-withdrawing nature of both the fluorine and nitro groups. The presence of these substituents induces an increase in electrophilicity, making the benzene ring more susceptible to nucleophilic attack. Consequently, 3,4-difluoronitrobenzene serves as a valuable intermediate in the synthesis of various chemical compounds, particularly those with biological applications.
- Its physical properties include a melting point of around 50 degrees Celsius and a boiling point of approximately 190 degrees Celsius.
- Additionally, it possesses limited solubility in water but is dissolvable in common organic solvents.
The synthesis of 3,4-difluoronitrobenzene typically involves a multi-step process which includes the nitration of fluorobenzene followed by precise fluorination. This compound has been widely studied due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Synthesis and Properties of 3,4-Difluoronitrobenzene
3,4-Difluoronitrobenzene possesses a significant role in the realm of organic synthesis due to its unique structural characteristics. The synthesis of this compound can be achieved through various routes, with a commonly employed method involving the nitration of 1,2-difluorobenzene. This reaction typically utilizes a mixture of nitric acid and sulfuric acid as the nitrating agent, producing the desired 3,4-difluoronitrobenzene product.
The resulting compound exhibits distinct physicochemical properties that influence its reactivity and applications. Notably, the electron-withdrawing nature of the nitro group in 3,4-difluoronitrobenzene alters its electrophilicity, making it susceptible to nucleophilic attack. This property renders it a versatile building block for the synthesis of complex organic molecules.
- Furthermore, the presence of fluorine atoms in the molecule contributes to its durability and dissolvability in various solvents.
CAS No. for 3,4-Difluoronitrobenzene: Identifying This Compound
When working with chemicals, accurately pinpointing them is crucial for safety and correct results. A key tool in this process is the CAS Registry Number, a unique identifier assigned to every chemical compound. For 3,4-Difluoronitrobenzene, this number is vital for ensuring you are working with the correct substance.
The CAS No. for 3,4-Difluoronitrobenzene is 105387-96-3. This unique identifier can be used to locate information about the compound in databases read more and reference materials. Understanding its properties, hazards, and safe handling procedures is paramount when dealing with this chemical.
Applications of 3,4-Difluoronitrobenzene in Research
3,4-Difluoronitrobenzene demonstrates a extensive variety of applications in research. Its unique arrangement and physical properties permit it to be utilized as a valuable precursor in the synthesis of novel organic compounds. Researchers utilize 3,4-difluoronitrobenzene for its reactivity in producing new materials with desired properties. Furthermore, this compound acts as a useful tool in the study of chemical processes. Its capabilities extend diverse research areas, including materials science.
Safety Considerations for Handling 3,4-Difluoronitrobenzene
When manipulating 3,4-difluoronitrobenzene, it is critical to prioritize safety. This substance can be hazardous if not treated properly. Always perform operations in a well-ventilated space and don appropriate safety gear, including nitrile gloves, safety glasses, and a coveralls.
Before handling with 3,4-difluoronitrobenzene, carefully review the hazard information provided by the provider. This guide will provide detailed information on potential hazards, first treatment, and storage procedures.
- Avoid interaction with skin. In the event of incidence, immediately flush the region with copious amounts of running water for at least quarter hour.
- Store 3,4-difluoronitrobenzene in a tempered area away from ignition points and incompatible materials.
- Dispose of 3,4-difluoronitrobenzene properly in accordance with applicable laws.
Spectral Characterization of 3,4-Difluoronitrobenzene
The spectral characterization of this fluorinated nitroarene is crucial for elucidating its chemical properties and potential applications.
Infrared|UV-Vis|NMR spectroscopy provides valuable insight into the vibrational modes, electronic transitions, and nuclear structure of this compound.
The distinct spectral features observed can be assigned to the presence of the nitro group, fluorine atoms, and benzene ring. Intensive spectral analysis reveals the influence of these substituents on the overall molecular polarity.
This thorough spectral characterization improves our understanding of DFNB and its potential application in various chemical reactions.